ІНСТ = 56;УКЦІЯ

д&= #1083;я медичного застосуванl= 5;я лікарськогl= 6; засобу

&nb= sp;

(NEIRAXIN^® B)

&= #1057;клад:

д&= #1110;ючі речовини: pyrido= xine, thiamine, cyanocobalamin, lidocaine;

<= span style=3D'mso-bidi-font-size:12.0pt;mso-fareast-font-family:"Times New Roman= "; mso-fareast-language:RU;mso-bidi-font-weight:bold;mso-bidi-font-style:itali= c'>2 мл розчину (1 ампула) міст= 103;ть піридоксинm= 1; гідрохлориk= 6;у (вітаміну В_{6) —
100 мг, тіаміну k=
5;ідрохлорид=
091;
(вітаміну В_{1) —
100 мг,
ціанокобалk=
2;міну
(вітаміну В_{12)
— 1 мг,
лідокаїну г=
10;дрохлориду
— 20 мг;}}}

д&= #1086;поміжні речовини

Лікарсь&= #1082;а форма. Розчин для ін’єкцій.=

Основні фізико-хімі = 95;ні властивостo= 0;:

Ф&= #1072;рмакотерап= ;евтична група. = Препарати вітаміну В₁ у комбінаці= 11; з вітаміном = 042;₆та/або вітаміном В12. Код АТХ А11D В.

&= #1060;армакологі= ;чні властивостo= 0;

<= o:p>

aabКлінічн&= #1110; характерисm= 0;ики

П&= #1086;казання.<= span style=3D'mso-bidi-font-size:12.0pt;mso-fareast-font-family:"Times New Roman= "; mso-fareast-language:RU'> С&= #1080;стемнi неврологічl= 5;і захворюванl= 5;я, спричинені встановленl= 0;м дефіцитом вітамінів B_{1,
B₆ і B₁₂, якщо =
081;ого
не можна усу=
085;ути
дієтичним
харчуванняl=
4;.}

П&= #1088;отипоказан= ;ня

Підв = 80;щена чутливість до компонентіk= 4; лікарськог&#= 1086; засобу; гост= 088;е порушення с = 77;рцевої провідностo= 0;; гостра форма декомпенсоk= 4;аної серцевої недостатноl= 9;ті.

Віта = 84;ін В₁ — протипоказk= 2;но при алергічних реакціях.=

Віта = 84;ін В₆₌Віта = 84;ін В₁₂— = протипоказk= 2;но застосовувk= 2;ти при еритрем= 10;ї, еритроцитоk= 9;і, тромбоембоl= 3;ії.

Лідо = 82;аїн — протипоказk= 2;но застосовувk= 2;ти при підвище = 85;ій індивідуалn= 0;ній чутливості до лідокаїн = 91; або до інших амідних місцевоанеl= 9;тезувальни= 093; засобів, при &#= 1085;аявності в анамнезі епілептифоl= 8;мних судом на лід= 086;каїн, при тяжкій брадикардіo= 1;, тяжкій артеріальнo= 0;й гіпотензії, кардіогеннl= 6;му шоку, тяжких формах хронічної серцевої недостатноl= 9;ті (ІІ–ІІІ ступеня), синдромі слабкості синусового вузла, синдромі Вольфа — Пар= 082;інсона — Уайта, сидромі Адамса — Сто= 082;са, атріовентрl= 0;кулярній блокаді ІІ і ІІІ ступеня, гіповолеміo= 1;, тяжких порушеннях функції печінки/нир = 86;к, порфірії, міастенії.=

Пері = 86;д вагітності та грудного = 075;одування.

В&= #1079;аємодія з іншими лікарськимl= 0; засобами та інші види взаємодій<= /b>О&= #1089;обливості застосуванl= 5;яНейр = 72;ксин^® B містить лідокаїну гідрохлориk= 6;, і тому лікар= 089;ький засіб слід вводити лиш = 77; внутрішньо&= #1084;’язово. Не дозволяєтьl= 9;я внутрішньоk= 4;енне (в/в) введення у кровоносн = 91; систему. У випадку помилкової внутрішньоk= 4;енної ін’єкції, залежно від ступеня важкості виниклих симптомів, п= 086;трібен медичний контроль аб = 86; спостережеl= 5;ня в стаціонар = 85;их умовах. Довг= 086;тривале, понад 6 місяців, застосуванl= 5;я лікарськогl= 6; засобу може призвести д = 86; оборотної периферичнl= 6;ї сенсорної нейропатії.

З&= #1072;стосування у період вагітності або годуван = 85;я груддю

міст = 80;ть 100 мг вітаміну В₆ на ампулm= 1;, тому його не слід застосовувk= 2;ти у період вагітності = 72;бо годування груддю.

З&= #1076;атність впливати на швидкість реакції при керуванні автотранспl= 6;ртом або іншими механізмамl= 0;.

&= #1057;посіб застосуванl= 5;я та дози

&nb= sp;

П&= #1077;редозуванн= ;я10 г) = 74;иявляють курареподіk= 3;ний ефект, пригнічуючl= 0; провідністn= 0; нервових імпульсів.

1 = г на добу протягом кількох місяців мож = 77; призвести д = 86; нейротоксиm= 5;них ефектів.

Не&= #1074;ропатії з атаксією і розлади чутливості, церебральнo= 0; конвульсії зі змінами н= 072; електроенцk= 7;фалограмі (ЕЕГ), а також в окремих випадках гіпохромна анемія і себорейний дерматит були описан= 10; після введе= ння більше 2 г на добу.

Вітамін В₁₂: після парентералn= 0;ного введення (у рідкісних випадках — після пероральноk= 5;о застосуванl= 5;я) доз препара = 90;у вищих, ніж рекомендовk= 2;ні, спостерігаl= 3;ись алергічні реакції, екзематознo= 0; шкірні порушення і доброякіснk= 2; форма акне.

Лікуван&= #1085;я: терапія симптоматиm= 5;на.

Симптом&= #1080; передозуваl= 5;ня лідокаїну:= Лікуван&= #1085;я:<= o:p>

П&= #1086;бічні реакції=

дуже часто: ≥ 1/10;

ч&= #1072;сто: від ≥ 1/100 до < 1/10;

н&= #1077;часто: від ≥1/1000 до <1/100;

р&= #1110;дко: від ≥ 1/10.000 до < 1/1.000;

д&= #1091;же рідко: < 1/10.000;

н&= #1077;відомо: частоту неможливо оцінити на основі наяв = 85;их даних.

Повідом= ;лення про підозрюванo= 0; побічні реа = 82;ції

Повідом= ;лення про побічні реакції після реєст = 88;ації лікарськогl= 6; засобу ма велике = 79;начення. Це дає змогу проводити м = 86;нiторинг співвідношk= 7;ння користь/риз = 80;к при застосу = 74;анні цього лікарськогl= 6; засобу. Медичним та фармацевтиm= 5;ним працівникаl= 4;, а також паці= 108;нтам або їхні = 84; законним представниl= 2;ам слід повідо = 84;ляти про усі випадки під = 86;зрюваних побічних ре = 72;кцій та відсутно = 89;ті ефективносm= 0;і лікарськогl= 6; засобу чере = 79; Автоматизоk= 4;ану інформаційl= 5;у систему з фармаконагl= 3;яду за посиланням: https://aisf.dec.gov.ua

Т&= #1077;рмін придатностo= 0;.&= #1053;есумісніст= ;ь

Виробни&= #1082;, який відповідає = 79;а випуск сері= 11;: АТ «Калцекс».

Місцезн&= #1072;ходження виробника т = 72; адреса місця прова = 76;ження його діяльн = 86;сті

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